FORMATION POTENTIAL SCREENING TESTS FOR INDUSTRIAL CHEMICALS

Identification of potential aryl hydrocarbon receptor ligands by virtual screening of industrial chemicals

We have developed a virtual screening procedure to identify potential ligands to the aryl hydrocarbon receptor (AhR) among a set of industrial chemicals. AhR is a key target for dioxin-like compounds, which is related to these compounds' potential to induce cancer and a wide range of endocrine and immune system-related effects. The virtual screening procedure included an initial filtration aimi...

Industrial Chemicals

In vitro screening for angiostatic potential of herbal chemicals.

PURPOSE Herbal medicine has long been used in traditional medicinal systems. The authors carried out a first-line screening of four herbal chemicals with reported antioxidative properties and capabilities to suppress endothelial cell growth and migration. These herbal chemicals were isoliquiritigenin (ISL) from licorice, epigallocatechin gallate (EGCG) from green tea, resveratrol (Rst) from gra...

Does The Standard Toxicological Testing Paradigm for Industrial Chemicals Apply to Screening for Children’s Health Risks?

Questions have been raised concerning whether standard toxicological testing paradigms for characterizing hazards are applicable for children. In this paper, the standard toxicological testing paradigm for industrial chemicals is examined. The analysis includes examination of the basic principles and elements of hazard characterization methodology based on animal toxicity data, examination of t...

Review of Autism Screening Tests

Background: Autism is a neurodevelopmental disorder that onset in the first 3 years of life and led to lifelong disability.Despite the early onset of symptoms, diagnosis of thissyndromedoes not happenuntil severalyears later, somany childrenlosethe opportunityfor earlyintervention.There arevarious toolsforscreening anddiagnosis, buttheirdesign, strengths and weaknesses aredifferent. The aim of ...